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Alternating hemiplegia of childhood (AHC) is a very rare disorder that causes paralysis that freezes one side of the body and then the other in devastating bouts that arise at unpredictable intervals. Seizures, learning disabilities and difficulty walking are common among patients with this diagnosis.
Researchers at Duke University Medical Center have now discovered that mutations in one gene cause the disease in the majority of patients with a diagnosis of AHC, and because of the root problem they discovered, a treatment may become possible.
The study was published online on July 29 in Nature Genetics.
AHC is almost always a sporadic disease, which means that typically no one else in the family has the disease, said Erin Heinzen, Ph.D., co-author of the study and Assistant Professor of Medicine in the Section of Medical Genetics. "Knowing that we were looking for genetic mutations in children with this disease that were absent in the healthy parents, we carefully compared the genomes of seven AHC patients and their unaffected parents. When we found new mutations in all seven children in the same gene we knew we had found the cause of this disease."
All of the mutations were found in a gene that encodes ATP1A3, one piece of a key transporter molecule that normally would move sodium and potassium ions across a channel between neurons (nerve cells) to regulate brain activity.
In a remarkably broad international collaborative effort, the authors partnered with three family foundations (USA, Italy and France), including scientists from 13 different countries, to study an additional 95 patients and showed over 75 percent had disease-causing mutations in the gene for ATP1A3.
"This study is an excellent example of how genetic research conducted on a world-wide scale really can make a difference for such a rare disorder as AHC," said Arn van den Maagdenberg, Ph.D., and co-author on the study and geneticist from Leiden University Medical Centre in the Netherlands. "It truly was an effort from many research groups that led to this remarkable discovery."
"This kind of discovery really brings home just what the human genome project and next-generation sequencing have made possible," said David Goldstein, Ph.D., Director of the Duke Center for Human Genome Variation and co-senior author on the study. "For a disease like this one with virtually no large families to study, it would have been very difficult to find the gene before next-generation sequencing."
"Ideally what you want from a study like this is a clear indication of how the mutations change protein function so you know how to screen for drugs that will restore normal function or compensate for the dysfunction," said Goldstein, who is also a Professor in Duke Molecular Genetics and Microbiology. "While there is considerably more work to do, our initial evaluation of the mutations suggests that they may alter the behavior of the transporter pump as opposed to reducing its activity, as do other mutations in the gene that cause a less severe neurological disease."
Co-senior author Mohamad Mikati, M.D., Professor of Pediatrics and of Neurobiology, and Chief of Pediatric Neurology at Duke, said, "Many years ago my work with other collaborators on a family with this disease proved that AHC can be caused by genetic factors, but until now we did not know the underlying gene abnormality.
"The finding that ATP1A3 mutations cause AHC will increase awareness of the disease and the ability to accurately diagnose patients," Mikati said. "While it may take a while for novel drugs to be developed to better treat this disease, we will see an immediate impact through specific testing for mutations in this gene when we suspect a case of AHC. This direct testing will prevent misdiagnoses that too often have caused patients to be treated with inappropriate medications."
###
Duke University Medical Center: http://www.dukemednews.org
Thanks to Duke University Medical Center for this article.
This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.
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Lake Zurich Foreclosures are homes that are already owned by the bank. The foreclosure has happened. They are not short sales and they are not pre-foreclosures. You can search online at many of the foreclosure portal sites but they are not as up to date as we are. We only show Lake Zurich foreclosures that are for sale. Not those in the future or those closed.
It might surprise you to see how few there are but rest assured all the Lake Zurich foreclosures are all right here. If you are looking for Lake Zurich foreclosures, bookmark this page and come back frequently to look at new listings. Buying a bank owned home requires more knowledge on the part of your Lake Zurich Realtor, we would be happy to help you buy any of the homes you see here on this page.
Of course if you have any questions, give us a call.
View all the available bank owned - foreclosures for sale in Lake Zurich and see if there is a deal for you.
?2012 MRED LLC. All Rights Reserved.
The data relating to real estate for sale on this website comes in part from the Broker Reciprocity program of Midwest Real Estate Data LLC. Real Estate listings held by brokerage firms other than Royal Advocate Realty are marked with the MRED Broker Reciprocity logo or the Broker Reciprocity thumbnail logo (the MRED logo) and detailed information about them includes the names of the listing brokers. Some properties which appear for sale on this website may subsequently have sold and may no longer be available. Information Deemed Reliable but Not Guaranteed. The information being provided is for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.
MRED LLC data last updated at July 31, 2012 3:16 PM CT
Etihad Airways, the United Arab Emirates carrier, said Monday it has signed a codeshare agreement with Aer Lingus, two months after it acquired a small stake in the Irish airline.
"Etihad Airways and Aer Lingus have signed an historic interline and codeshare agreement which follows the UAE national airline?s recent 2.987 per cent equity purchase in the Irish carrier," it said in a statement.
The agreement will allow Etihad to fly its passengers arriving in Dublin on Aer Lingus flights to London, Manchester or other destinations in Ireland, Portugal, the Netherlands and the United States.
In exchange, Aer Lingus passengers arriving in Abu Dhabi will be able to board Etihad flights for Australia, Asia and the Middle East.
Etihad currently has 10 flights a week to Dublin.
It announced on May 1 that it had acquired a stake of 2.987 percent in Aer Lingus, adding to its 30 percent controlling interest in airberlin and 40 percent holding in Air Seychelles.
With a fleet of 67 aircraft, it flies to 87 passenger and cargo destinations worldwide. It has ordered another 100 planes, including 10 Airbus A380s.
In a country with diverse race, creed and ethnicity, yet cultural and racial cohesion remains a scarce commodity. A sense of community among the people of London needs improvement just like many of the major cities in the world.
Source: assistnews.net | 2012-07-30 - 3?hours ago
One of our senior leaders has been abducted by a terrorist group, and they are demanding a very high ransom for his release.
Source: assistnews.net | 2012-07-30 - 3?hours ago
God?s work in Africa is building momentum, and like always we are trying to keep up! Here are 75 more photos to show what it?s like, this time with our beautiful new ten-place Quest Kodiak aircraft that Jesus gave us through the gifts of so many...
Source: assistnews.net | 2012-07-30 - 3?hours ago
Rudwan Dawod, an American resident, NGO aid worker, humanitarian and pro-democracy activist, who worked closely with former NBA Legend Manute Bol, continues to be on trial Sunday, July 29 in Khartoum, Sudan...
Source: assistnews.net | 2012-07-30 - 3?hours ago
Two Iranian Christian children, whose parents are being held in prison for their faith in Christ, are having to work to pay for their living expenses and then send half of their earnings for their parents in prison...
Source: assistnews.net | 2012-07-30 - 3?hours ago
The world was agog with the London Olympic Opening Ceremony which gave a presentation of a mix of British humor and the social mores of the development of the nation and in so doing industrialist Isambard Kingdom Brunel was presented preaching...
Source: assistnews.net | 2012-07-30 - 3?hours ago
Who could not recall the great Ethiopian 10,000 meter runner at the Sydney Olympics Haile Gebrselassie who having won the Gold Medal, and demonstrating his personal love for the Lord Jesus, and within the culture of his Christian Coptic communit...
Source: assistnews.net | 2012-07-30 - 3?hours ago
The well-known couple began attending a little Beijing house church regularly in 2005. This was different because they were part of the Communist Party. Later that year the couple quit the Communist Party and publicly called it ?inhuman, unjust,...
Source: assistnews.net | 2012-07-29 - 23?hours ago
A one-time Australian rock star who is now a missionary in Sierra Leone, has told the ASSIST News Service the extraordinary story of a victim of shocking ?war crimes? in this country.
Source: assistnews.net | 2012-07-29 - 23?hours ago
The Japanese 13-member collective known as Heavenese will be returning to U.S. October 17th through November 4th to play several shows across the country including stops in Los Angeles, Dallas and Kansas City the group announced...
Source: assistnews.net | 2012-07-29 - 1?day ago
Pastor Behnam Irani, currently held in Ghezal Hesar prison in Iran, is being denied hospital treatment for severe bleeding due to stomach ulcers and complications with his colon.
Source: assistnews.net | 2012-07-29 - 1?day ago
Galilee of the Nations Music says Aug. 7 will be the launch date for its five-volume The Names of God series, which includes the CDs Adonai, Elohim, Yeshua, Sar Shalom and Son of David.
Source: assistnews.net | 2012-07-29 - 1?day ago
Vatican Radio is reporting that amid the growing international campaign demanding release of Asia Bibi, a Church official in Pakistan said the local Church would prefer to maintain a solemn, prayerful vigil.
Source: assistnews.net | 2012-07-28 - 2?days ago
40 years ago I gathered with a 5,000 soul packed hometown city auditorium to witness a remarkable moment of evangelism. Only 40 miles from Canada in North Central - North Dakota, Minot only boasted a little over 30,000 inhabitants at the time...
Source: assistnews.net | 2012-07-28 - 2?days ago
On Friday morning (July 27, 2012), just hours before the opening ceremony of the London 2012 Olympic Games, Consul General of Israel David Siegel, convened local officials and community leaders at the Los Angeles Memorial Coliseum, site of the 1...
Source: assistnews.net | 2012-07-28 - 2?days ago
Christian Men s Network (www.cmnworld.com) will celebrate 35 years of building strong men at ?Meet Me at the Jetty,? a celebratory gathering honoring over three decades of work, the 30th birthday of the best...
Source: assistnews.net | 2012-07-28 - 2?days ago
As the much-awaited Olympics have been launched in London, UK on July 27, 2012, Pakistanis, like other nationalities, are also very excited to watch their players show their best performance in the Games and send a message of peace to the world.
Source: assistnews.net | 2012-07-28 - 2?days ago
A 70-day Prayer Relay, which has tracked the route of the Olympic Torch Relay, will have its final stop at Westminster today (Thursday, July 26th), bringing it to the heart of British political life.
Source: assistnews.net | 2012-07-28 - 2?days ago
As the world watches with rapt attention the opening ceremonies of the 2012 London Olympic Games, Tim Stafford, senior writer for ?Christianity Today?, will be among the proud parents with a son or daughter competing in this latest Olympiad.
Source: assistnews.net | 2012-07-28 - 2?days ago
Greece has had its share of adverse publicity in the past few years. Many are fearful that it will default on its financial obligations. Others feel that it might withdraw from the Euro and head back to the bad old days of the drachma...
Source: assistnews.net | 2012-07-28 - 2?days ago
According to Bill Koene, president of www.Christian-audiobooks.com , ?We are currently witnessing a technological revolution in World Missions.?
Source: assistnews.net | 2012-07-28 - 2?days ago
Dudu Fisher began his vocal career in his native country of Israel, where he studied at the Tel Aviv Academy of Music.
Source: assistnews.net | 2012-07-28 - 2?days ago
Three internationally known designers and experienced trainers will be the 2012 design track training team for Magazine Training International s (MTI) five-day Advanced Magazine Publishing Institute this Fall in India.
If you are looking for Bastrop foreclosures in this area of Texas, you can find them right online. This is where you will find all of the listings for foreclosure properties including Del Valle foreclosures as well. When you are looking for property, the best way to get a good deal is to look for foreclosures. These are properties that have been taken over by the bank because someone has defaulted on their mortgage. As there are more homes on the market than there are buyers, now is the perfect time for buyers to get a bargain in the state of Texas when it comes to real estate, especially if they are looking in the foreclosure markets such as the Bastrop foreclosures or the Del Valle foreclosures.
There are many different properties that you can get when you are seeking out Bastrop foreclosures or Del Valle foreclosures. You can opt for single family homes or multi family homes as well as vacant properties, rental properties and even commercial real estate. Some of the foreclosure listings need work and most are sold as is. Before you set out to buy Del Valle foreclosures or Bastrop foreclosures, you need to figure out how much you have to spend and get any financing together.
You go through a realtor when you are buying Bastrop foreclosures or Del Valle foreclosures just as you would if you were buying property in any other way. However, because these properties are sold as is, it is a good idea to get an inspection done prior to putting in an offer for the house. Due diligence such as getting a title commitment for the property should be done at the time as well to make sure that there are no problems with the title. This is standard practice when buying any type of real estate but is usually done beforehand when buying foreclosure properties.
Going online and looking for Bastrop foreclosures as well as Del Valle foreclosures is easy. In addition to these, when you go onto a website that lists the foreclosure properties in Texas, you can do a search for the properties based on price, type of home that you are looking for and the area where you are seeking the home. You will then be able to pull up all of the Del Valle foreclosures or Bastrop foreclosures that are in your price range as well as are the type of property that you are looking for.
Once you find the Bastrop foreclosures or Del Valle foreclosures that interest you, you can contact the real estate agent and make an appointment to see the properties. They will take you through the properties at which time you can then decide if you want to place an offer. Placing an offer on the Bastrop foreclosures or Del Valle foreclosures is done through a real estate agency and then is presented to the bank for approval. If you are ready to close and have the money as well as make a reasonable offer, chances are that you will be able to purchase a home of your own in Bastrop or Del Valle.
Travel is in the middle of a sense of glamor. This is a widespread wish to see considerably off places, meet extraordinary people, expertise splendor and venture. Our journey desires will probably come true if we engage in meticulous planning. Listed here are tips to help you make vacation more fun.
In case you are vacationing with kids, permit them the ability to acquire some exercise before you decide to bring these people to your accommodation. It can be hard for the kids to journey on an airplane or in the car for a long period of energy. Try to find a playground to avoid at or enable your youngster to swim in the swimming pool area after you can the resort. This helps them loosen up following the night time.
If you use a backpack to keep points in whilst you travel, it is often a much better strategy to pack the lighter products at the end of your package and also the weightier items on top mainly because it can certainly make the back pack more at ease on the spinal column and make it easier to hold for the extensive length of time.
To get the most from your holiday, make databases and follow them. You?ll have only numerous vacation days and nights, so effective time management is essential to obtain the maximum benefit from your journey. After all, it is possible to get preoccupied from your primary trip desired goals. Begin with composing a summary of the things you need to see and do, such as specific sites to see, and then make use of the list to maintain you on path.
Check out your passport and electronic mail a copy to yourself. It seldom takes place, nevertheless in the opportunity that you just lose your passport during your moves, this can be a lifesaver. Receiving a substitute passport could be a headaches and achieving a copy will make the process much faster and much less disturbing.
If you are planning over a definitely far off and unique vacation of your life, look at buying an insurance plan that will include emergency evacuation, rescuing and look. The far away from society you plan to become, the greater happy you may be to have this kind of insurance.
Search out coupon codes and bargains. Before you established off for your spot, conduct an in depth Google search for destination and diner discounts. Monthly or two before leaving, subscribe to a neighborhood deals flash website for your personal location to credit score some terrific special discounts. Also you can check into investing in a voucher publication for your personal location. Explore the coupons it has and determine if the price of it are often more than made during the cash you?ll preserve.
Depending on your spot, consider buying toiletries when you arrive. This lowers the sum you must package and might save you money in case you have a lot fewer totes to confirm having an airline. It also lessens the time it takes to browse through airport safety because you are not having all the.
While you are traveling by cruise liner, require a snapshot along to wear your door. It is possible to get confused and also have issues tracking down your living area. All the hallways and doorways around the deliver appear very similar to one other. To help you locate any room without having hassle, place a photo of something you already know well upon it. Just take care not to put any personal photographs up.
Now that you?ve got a number of the essentials on traveling, inform your boss you take a holiday, buy your aeroplane ticket, vessel ticket or whatever means you intend on taking and go!
Remember to always be safe whether or not touring by itself or otherwise. Require guidelines and support if you require it. Most people is not going to mouthful. First and foremost,
When you stick to the suggestions we certainly have presented for you personally in the following paragraphs, you should be able to take at the very least several of the stress away from your trip. Every single trip includes its unique highs and lows and factors you can?t management, but furnished with helpful advice and shrewd recommendations, it is possible to decrease your worrying, and increase your relaxation and enjoyable.
Workgroup Manager and Managed Preferences are alive and kicking in Mountain Lion Server.
In addition to launching Mountain Lion Server last week, Apple rather quietly released a Mountain Lion Server version of Workgroup Manager ? the traditional Mac management tool included in previous releases of OS X Server. The move was unexpected after Apple released the Advanced Administration guide for Mountain Lion Server, which implied that administrators would need to begin an almost-immediate shift to Mountain Lion Server?s Profile Manager.
The move is good news for many organizations that have an existing investment in OS X Server and Mac clients. Although Mountain Lion Server?s Profile Manager is arguably a more modern and enterprise-friendly solution, it only supports Macs running Lion and Mountain Lion. Any schools or businesses with clients still on Leopard or Snow Leopard would be out of luck if Profile Manager were the only available option.
While the move is good news, there is very real probability that the Mountain Lion release of Workgroup manager is meant to offer a stop-gap measure for organizations that still rely heavily on Managed Preferences. Given that Workgroup Manager isn?t mentioned in Apple?s advanced admin documentation and the emphasis that the company is placing on Profile Manager and configuration profiles, it seems likely that Apple won?t provide Workgroup Manager and related features in whatever OS X Server release follows Mountain Lion Server.
Apple?s move to an annual release cycle for OS X (and presumably OS X Server) means that Workgroup Manager and Managed Preferences could be gone for good within a year. Following the cancellation of the Xserve and what could be called the consumerization of OS X Server since the release of Snow Leopard Server three years ago, many organizations dependent on OS X Server, Open Directory, Managed Preferences, and other enterprise-focused technologies have wisely begun to consider their options moving forward.
Lion Server could be seen as a nudge to prompt organizations to seriously consider if a release of OS X Server more oriented to small businesses or workgroups would meet their needs and to evaluate and implement alternative enterprise solutions if it isn?t.
Mountain Lion Server, with its more polished and production-ready capabilities certainly poses that same question and it should motivate Mac IT professionals working with OS X Server to really look at the release and the management capabilities of Profile Manager as well as third-party alternatives. That investigation will likely lead to developing a strategic plan for Mac management and/or support that extends further than the next six to twelve months (at least).
It?s worth noting, however, that Mountain Lion?s focus on configuration profiles has led mobile management vendors to add Mac management as an option right next to iOS, Android, and other mobile platform management tools. Mobile management vendor?AirWatch, for example, already supports Mac management and rival MobileIron?plans ?to integrate Mac management into a seamless administration console and workflows. That gives Mac IT pros more choices than ever before as they consider what solutions will be best for their organizations going forward.
I am trying to make a login script for my android application, the script will send my email and password to the PHP server, verify the login and then create a PHP session so that the user stays logged in. This is my code,
HttpPost httppost = new HttpPost("http://server.com/login.php"); // Create a new HttpClient and Post Header HttpClient httpclient = new DefaultHttpClient(); public String login() { String userID = ""; try { // Add your data List<NameValuePair> nameValuePairs = new ArrayList<NameValuePair>(2); nameValuePairs.add(new BasicNameValuePair("email", "e@e.com")); nameValuePairs.add(new BasicNameValuePair("password", "admin")); httppost.setEntity(new UrlEncodedFormEntity(nameValuePairs)); // Execute HTTP Post Request HttpResponse response = httpclient.execute(httppost); userID = EntityUtils.toString(response.getEntity()); //Log.v("Login response", "" + userID); } catch (ClientProtocolException e) { // TODO Auto-generated catch block } catch (IOException e) { // TODO Auto-generated catch block } return userID; }
This script successfully sends data to my server and my PHP successfully logs the user on. I have placed "HttpClient httpclient = new DefaultHttpClient();" outside my main login method. This has helped store the session until I call upon another class, then it just resets the session again. So I am wondering how I can alter the code so that "httpclient" is somehow stored so I can keep the session and stay logged into my server. Thank you!
This is my 2nd attempt at sharing the learning that occurs at and that which can be gleaned from reading about committee meetings. As always, discussion and questions are welcome.
Meeting held: Friday, July 27th at 10am-12:30pm
In attendance: Lisa McKenney (ACLS), Chris McGee (ACLS), Cathy Ashby (RELIB), Bonnie Winters (RELIB), Elizabeth Hulett (WCFL), Bill Taylor (WCFL), Joe Thompson (Chair, WMRL), and Julie Zamostny (note-taker, WMRL)
Presentation by Monica Wilson, Gale Databases Representative Monica provided a 40 minute overview of some of the lesser-known features of the Gale Virtual Reference Library (GVRL). Below are some of the highlights.
Unlimited simultaneous use; 24/7 access with authentication via library barcode
Articles are downloadable to eReaders and tablets; Kindle users must know their Kindle email to take advantage of this feature
MARC records are available so that GVRL titles display in the PAC = increases discoverability
Articles can be read aloud in 19 languages
Articles can be downloaded in MP3 format
Articles can be viewed in enriched text and PDF
Ability to download up to 50 titles at once
New and improved Help Guides with text and video
Can create a GVRL username and password so you can save articles in folders for retrieval at a later date
Reminder: support.gale.com has a lot of helpful resources
GVRL can create special collections from the admin site or by contacting tech support. For example, they can create a collection of DK titles that libraries can then display/link to on their websites.
GVRL has an Access My Library app - still glitchy - use with caution. GPS authentication only, barcode authentication is not available through the Access My Library app.
?Review of December Meeting Minutes
Page 2: NextReads. Group recommended that Joe get a quote from EBSCO that would separate out NextReads from the other subscriptions so we can tell how much we're actually paying for it. All three counties still use it to some extent so, the intent is to continue to subscribe unless the cost is prohibitive.
LibraryThing has been officially dropped.
Lisa McKenney's and Emily Zumbrun's names were misspelled.
Minutes from the December meeting were approved.
Review of SAILOR Subscriptions
SAILOR databases have not changed, the contract with Gale expires June 2013
Committee would like to know when discussions will start regarding the renewal of the contract
Review of WMRL Subscriptions
eVanced scheduling software is now available and is being utilized by ACLS and WCFL. RELIB may work with ACLS to determine whether or not it is the right product for their needs.
Mango Languages: Joe hasn't received an invoice yet but the intention is to renew
OverDrive Advantage funds goes to buying more copies of titles already owned plus buying unique titles that are not already in the OverDrive database. Lisa McKenney and Carrie Plymire (WMRL) are responsible for purchasing Advantage titles for the region.
MPERL has been dissolved and therefore we are now responsible for negotiating contracts for four databases: Gale packages, Testing and Education Resource Center, ValueLine, and one other that I missed.?
Committee recommended that Joe get quotes from EBSCO for comparable products: Biography Reference Center and Literary Reference Center
Compliance Suite expires in September. Julie Z, Jennifer Spriggs (ACLS), and Franny Lockely (WCFL) all use this software for librarian certification tracking. Intent is to renew.
Dropped OCLC due to shared ILS
?FY2012 Database Usage Stats
This is a little like combining apples and oranges because each database defines usage differently (i.e. page views, searches, downloads, etc.)
If you want to see raw database usage data, Joe will email you his extremely detailed spreadsheet.
Committee recommended that Joe see if he can separate out usage stats for NoveList Plus and NoveList Select Classic (this is what shows up automatically when you do a title search in the PAC). Committee would also like to look at pricing for each of these as separate entities.
Committee would like to recommend that we strongly encourage our respective children's departments to promote Little Pim (language learning database for kiddos)
Reference USA Discussion This was originally discussed as part of the FY2012 Database Usage Stats but since it is a recurring discussion I decided to give it a separate heading.
ACLS and RELIB do not see the value when examining the Cost: Use ratio (at a regional level)
WCFL staff rely on it heavily - and that is reflected in the usage stats (at the county level)
ACLS and RELIB feel like the information in RefUSA can be found easily on the Internet.
Cathy mentioned that, historically, the information contained within RefUSA has been out of date and inaccurate.
WCFL cannot afford the database on their own
ACLS and RELIB agree that it is not a matter of training that would help rectify the lack of usage in their counties.
Can WMRL pay for just WCFL to have this database and have WCFL act as clearinghouse for all things Business that are received across all three counties, similar to The Foundation Center (Note: WMRL does not pay for the Foundation Center database, it was only mentioned in the meeting as a comparison). This model would be cause for more in-depth discussion because of the possibilty of setting a precedence. Joe feels awkward about this because he strongly feels that WMRL should be paying for resources that are available and of use across all three counties.?
Final settlement: committee agrees to keep paying for it but it will continue to be a point of discussion for this committee
TRIALS Follow-Up
Access News: not interested
Zinio: not interested until it's iPad compatible
Universal Class: not interested, do not consider for 2 years
Dzanc Books: not interested
Proquest Historical Newspapers: not interested, do not consider for 2 years
Pronunciator: not interested, do not consider for 2 years
Muzzy: not interested
Axis360: not interested
3M ebooks: not interested until more information is available from BCPL (they're BETA testers)
Hoopla: there is interest around this; look at it after the Fall 2012 release
Committee is not looking to add anything new at this time be we'll consider any left over money to be used to enhance OverDrive or to purchase a new product later if we identify one.
Committee would like to consider using any leftover funds to promote the databases. This will be an agenda item at the next Spring meeting.
Newly formed MLC: Maryland Library Consortium. Joe might have to provide more information on this. The group's target is databases but it encompasses more than that.WMRL is participating.
GVRL Weeding
WCFL is purchasing their own GVRL ebook titles and they're happy to share with the rest of the group even though WMRL is not paying for region-wide access
Committee would like Joe to get quote from Gale regarding a special DK package and we want to know what the age of the titles is, then we'll decide if we want to trial. It was recommended that we talk with Harford County - they already have something comparable in place.
Joe will make his recommendatiosn to the group as to which titles he thinks should be withdrawn.?
In the van on the way home, Joe and Elizabeth decided that Elizabeth would take on this task instead.
We still want to receive the MARC records of the titles that are relevant.
?Discovery Services
Joe asks that the committee keep these services/products in mind when we're at conferences, etc. They aren't a top priority but he foresees possible interest in them in the future.
End of Meeting
Joe will Doodle the committee to determine the next 2 dates of meetings.
Public can explore time-lapse videos of Earth with new tool from Carnegie Mellon and Google Public release date: 30-Jul-2012 [ | E-mail | Share ]
Contact: Byron Spice bspice@cs.cmu.edu 412-268-9068 Carnegie Mellon University
13 years of Landsat imagery can be easily explored
PITTSBURGHResearchers at Carnegie Mellon University's Robotics Institute, working with colleagues at Google and the U.S. Geological Survey (USGS), have adapted their technology for interactively exploring time-lapse imagery to create a tool that enables anyone to easily access 13 years of NASA Landsat images of the Earth's surface.
This new capability within Google Earth Engine enhances the public's ability to view the massive amount of imagery collected by the Landsat program between 1999 and 2011. Users can zoom in or out on any spot on the globe and move back and forth in time. This enables anyone to see deforestation unfold in the Amazon, see water levels rise and fall in the Aral Sea and watch the urbanization of desert as Las Vegas expands.
For the past 40 years, the Landsat program has continuously collected imagery of the Earth's surface and, since 2008, the USGS has made that imagery available free to the public. But accessing that data measured in petabytes, or quadrillions of bytes has long been cumbersome, said Randy Sargent, a system scientist in the Robotics Institute's CREATE Lab in Pittsburgh and a visiting researcher at Google.
Google has improved access by building the largest library of Landsat imagery on hard-drive storage, Sargent said. Google Earth Engine has already amassed more than 1.5 million Landsat images of Earth and this is growing by thousands of images per day as new satellite data is collected.
The new tool for Earth Engine, based on Carnegie Mellon's GigaPan Time Machine technology, takes this access to another level. When combined with Google Earth Engine's massively parallel computation power, the Landsat image archive is transformed into a set of seamless, zoomable videos easily accessible from a modern Web browser.
"The sheer volume of visual data is daunting to explore by conventional means," said Rebecca Moore, engineering manager of Google Earth Engine. "Together we can now offer an intuitive, effortless method to explore the planet in space and time."
Google, NASA and Carnegie Mellon previously collaborated to create GigaPan, a technology for capturing a mosaic of hundreds or thousands of digital pictures and stitching those frames into panoramas that be interactively explored via computer. GigaPan Time Machine, developed with Google's support, took advantage of the HTML5 language incorporated into such browsers as Google Chrome to extend GigaPan into the realm of video. Sargent, along with CMU colleagues Paul Dille and Chris Bartley, developed algorithms and software architecture that made it possible to shift seamlessly from one video portion to another as viewers zoom in and out of the imagery.
One of the first applications of the Time Machine technology was to 12 months of imagery from NASA's Moderate Resolution Imaging Spectroradiometer, or MODIS, satellites. Sargent said the success of that project led directly to the effort to create a tool for accessing Landsat and other satellite imagery available through Google Earth Engine.
Sargent predicted that the enhanced access to satellite imagery will help ground public discussions about land use, climate change and environmental policy. "You can continue to argue about why deforestation has happened," he explained, "but you no longer will be able to argue whether it happened.
"Exploring the data is now much faster hundreds of times faster than it used to be," he added. "That leads to discoveries. That leads to making connections."
###
Videos demonstrating how the time-lapse tool can be used to explore phenomena such as deforestation, urban growth and drying seas can be viewed at http://earthengine.google.org/#intro.
In addition to Sargent, Dille and Bartley, computer science student Richard Hofer, Robotics Institute intern Saman Amirpour and Illah Nourbakhsh, professor of robotics and director of the CREATE Lab, have contributed to this project. They are continuing to work with Google scientists to increase access to additional imagery from Landsat and other satellite programs.
The Robotics Institute is part of Carnegie Mellon's School of Computer Science. Follow the school on Twitter @SCSatCMU.
About Carnegie Mellon University:
Carnegie Mellon (www.cmu.edu) is a private, internationally ranked research university with programs in areas ranging from science, technology and business, to public policy, the humanities and the arts. More than 11,000 students in the university's seven schools and colleges benefit from a small student-to-faculty ratio and an education characterized by its focus on creating and implementing solutions for real problems, interdisciplinary collaboration and innovation. A global university, Carnegie Mellon's main campus in the United States is in Pittsburgh, Pa. It has campuses in California's Silicon Valley and Qatar, and programs in Asia, Australia, Europe and Mexico. The university is in the midst of "Inspire Innovation: The Campaign for Carnegie Mellon University," which aims to build its endowment, support faculty, students and innovative research, and enhance the physical campus with equipment and facility improvements.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public can explore time-lapse videos of Earth with new tool from Carnegie Mellon and Google Public release date: 30-Jul-2012 [ | E-mail | Share ]
Contact: Byron Spice bspice@cs.cmu.edu 412-268-9068 Carnegie Mellon University
13 years of Landsat imagery can be easily explored
PITTSBURGHResearchers at Carnegie Mellon University's Robotics Institute, working with colleagues at Google and the U.S. Geological Survey (USGS), have adapted their technology for interactively exploring time-lapse imagery to create a tool that enables anyone to easily access 13 years of NASA Landsat images of the Earth's surface.
This new capability within Google Earth Engine enhances the public's ability to view the massive amount of imagery collected by the Landsat program between 1999 and 2011. Users can zoom in or out on any spot on the globe and move back and forth in time. This enables anyone to see deforestation unfold in the Amazon, see water levels rise and fall in the Aral Sea and watch the urbanization of desert as Las Vegas expands.
For the past 40 years, the Landsat program has continuously collected imagery of the Earth's surface and, since 2008, the USGS has made that imagery available free to the public. But accessing that data measured in petabytes, or quadrillions of bytes has long been cumbersome, said Randy Sargent, a system scientist in the Robotics Institute's CREATE Lab in Pittsburgh and a visiting researcher at Google.
Google has improved access by building the largest library of Landsat imagery on hard-drive storage, Sargent said. Google Earth Engine has already amassed more than 1.5 million Landsat images of Earth and this is growing by thousands of images per day as new satellite data is collected.
The new tool for Earth Engine, based on Carnegie Mellon's GigaPan Time Machine technology, takes this access to another level. When combined with Google Earth Engine's massively parallel computation power, the Landsat image archive is transformed into a set of seamless, zoomable videos easily accessible from a modern Web browser.
"The sheer volume of visual data is daunting to explore by conventional means," said Rebecca Moore, engineering manager of Google Earth Engine. "Together we can now offer an intuitive, effortless method to explore the planet in space and time."
Google, NASA and Carnegie Mellon previously collaborated to create GigaPan, a technology for capturing a mosaic of hundreds or thousands of digital pictures and stitching those frames into panoramas that be interactively explored via computer. GigaPan Time Machine, developed with Google's support, took advantage of the HTML5 language incorporated into such browsers as Google Chrome to extend GigaPan into the realm of video. Sargent, along with CMU colleagues Paul Dille and Chris Bartley, developed algorithms and software architecture that made it possible to shift seamlessly from one video portion to another as viewers zoom in and out of the imagery.
One of the first applications of the Time Machine technology was to 12 months of imagery from NASA's Moderate Resolution Imaging Spectroradiometer, or MODIS, satellites. Sargent said the success of that project led directly to the effort to create a tool for accessing Landsat and other satellite imagery available through Google Earth Engine.
Sargent predicted that the enhanced access to satellite imagery will help ground public discussions about land use, climate change and environmental policy. "You can continue to argue about why deforestation has happened," he explained, "but you no longer will be able to argue whether it happened.
"Exploring the data is now much faster hundreds of times faster than it used to be," he added. "That leads to discoveries. That leads to making connections."
###
Videos demonstrating how the time-lapse tool can be used to explore phenomena such as deforestation, urban growth and drying seas can be viewed at http://earthengine.google.org/#intro.
In addition to Sargent, Dille and Bartley, computer science student Richard Hofer, Robotics Institute intern Saman Amirpour and Illah Nourbakhsh, professor of robotics and director of the CREATE Lab, have contributed to this project. They are continuing to work with Google scientists to increase access to additional imagery from Landsat and other satellite programs.
The Robotics Institute is part of Carnegie Mellon's School of Computer Science. Follow the school on Twitter @SCSatCMU.
About Carnegie Mellon University:
Carnegie Mellon (www.cmu.edu) is a private, internationally ranked research university with programs in areas ranging from science, technology and business, to public policy, the humanities and the arts. More than 11,000 students in the university's seven schools and colleges benefit from a small student-to-faculty ratio and an education characterized by its focus on creating and implementing solutions for real problems, interdisciplinary collaboration and innovation. A global university, Carnegie Mellon's main campus in the United States is in Pittsburgh, Pa. It has campuses in California's Silicon Valley and Qatar, and programs in Asia, Australia, Europe and Mexico. The university is in the midst of "Inspire Innovation: The Campaign for Carnegie Mellon University," which aims to build its endowment, support faculty, students and innovative research, and enhance the physical campus with equipment and facility improvements.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
The Center for Reproductive Rights. Washington, DC, USA.
Center Background:
The Center for Reproductive Rights (the Center) is a non-profit legal advocacy organization dedicated to advancing reproductive freedom as a fundamental right that all governments are legally obligated to protect, respect, and fulfill. The Center?s domestic and international programs engage in litigation, policy analysis, legal research, and public education seeking to achieve women?s equality in society and ensure that all women have access to appropriate and freely chosen reproductive health services. This position is based in Washington, DC.?
Responsibilities:
Law students are expected to have strong legal research and writing skills and an interest in gender/women?s issues and reproductive rights. ?Other responsibilities include:
Monitoring and responding to legislative and other political developments, including hearings, markups and other events;? ??
Drafting materials, including bill analysis, fact sheets, legislative drafting and legal memoranda, for use in lobbying activities and outreach and on the Web;? ??
Preparing internal and external updates, blog posts, op-eds and other written analysis.
Position Type: Internship. Approx. 12-35 hours per week during the fall or spring semesters, 35 hours per week in the summer (flexible according to your schedule and school calendar).
To Apply:
Please email (resumes@reprorights.org) a cover letter, resume, and a short writing sample via email (preferred). Applicants must indicate ? Legal Intern (based in DC), code 146 and last name? as the subject of emailed applications. Cover letter, resume, and writing sample should be sent as attachments.
Compensation: A small stipend may be available. We are also happy to work with institutions to secure academic credit when available.
1 in 5 streams damaged by mine pollution in southern West VirginiaPublic release date: 30-Jul-2012 [ | E-mail | Share ]
Contact: Tim Lucas tdlucas@duke.edu 919-613-8084 Duke University
DURHAM, N.C. -- Water pollution from surface coal mining has degraded more than 22 percent of streams and rivers in southern West Virginia to the point they may now qualify as impaired under state criteria, according to a new study by scientists at Duke and Baylor.
The study, published this week in the peer-reviewed journal Environmental Science & Technology, documents substantial losses in aquatic insect biodiversity and increases in salinity linked to sulfates and other pollutants in runoff from mines often located miles upstream.
"Our findings offer concrete evidence of the cumulative impacts surface mining is having on a regional scale," said Emily S. Bernhardt, associate professor of biogeochemistry at Duke's Nicholas School of the Environment. "The relationship is clear and direct. The more mining you have upstream, the higher the biological loss and salinity levels will be downstream, and the farther they will extend."
Numerous recent studies have demonstrated the water-quality problems caused at or near the site of individual surface coal mines, Bernhardt noted. She and her team "set out to understand how the large and growing number of surface mines is affecting water quality throughout Appalachia."
They used NASA satellite images and computer data to map the extent of surface mining taking place across a 12,000-square-mile area of the southern West Virginia coalfields between 1976 and 2005.
They found that companies had converted more than five percent of the land into mine sites and buried 480 miles of streams beneath adjacent valley fills during this period.
Chemical and biological data from 223 streams sampled by the West Virginia Department of Environmental Protection between 1997 and 2007 were combined with mapping to help the researchers determine that pollution runoff from the mines could substantially degrade more than 1,400 miles of streams in the region. That's four times the length of streams buried by the valley fills.
"It's important to recognize that surface coal mining pollution doesn't stop at mine-permit boundaries," said Brian D. Lutz, a postdoctoral associate in Bernhardt's lab.
"Our analysis suggests that mining only five percent of the land surface is degrading between 22 percent and 32 percent of the region's rivers," he said.
Substantial declines in insect diversity began to occur when companies had mined as little as one percent of upstream land, the analysis showed. In areas where companies had converted about five percent of the land into mines, sensitive species such as mayflies and stoneflies had vanished or declined to an extent that the streams would qualify as biologically impaired under criteria set by the state of West Virginia.
The designation means the streams could be placed on a list of waterways that the state must take steps to rehabilitate.
"What is so compelling is that we found many different types of organisms are lost downstream of surface coal mines, and most of them begin to disappear at similar levels of mining," said Ryan S. King, associate professor of biology at Baylor. "Our analysis shows that coal mining is leading to widespread declines in aquatic biodiversity in Appalachian streams."
###
Lutz and King co-authored the paper with Bernhardt. Other coauthors were John P. Fay, instructor of geospatial analysis at the Nicholas School; Catherine E. Carter, a 2010 master's graduate of the Nicholas School, now at TetraTech; Ashley M. Helton, postdoctoral associate in Duke's Department of Biology; John Amos of SkyTruth; and David Campagna, of Campagna & Associates.
The study was supported by unrestricted gifts in support of research from The Foundation for the Carolinas and the Sierra Club, and through a contract to Amos and Campagna from Appalachian Voices.
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1 in 5 streams damaged by mine pollution in southern West VirginiaPublic release date: 30-Jul-2012 [ | E-mail | Share ]
Contact: Tim Lucas tdlucas@duke.edu 919-613-8084 Duke University
DURHAM, N.C. -- Water pollution from surface coal mining has degraded more than 22 percent of streams and rivers in southern West Virginia to the point they may now qualify as impaired under state criteria, according to a new study by scientists at Duke and Baylor.
The study, published this week in the peer-reviewed journal Environmental Science & Technology, documents substantial losses in aquatic insect biodiversity and increases in salinity linked to sulfates and other pollutants in runoff from mines often located miles upstream.
"Our findings offer concrete evidence of the cumulative impacts surface mining is having on a regional scale," said Emily S. Bernhardt, associate professor of biogeochemistry at Duke's Nicholas School of the Environment. "The relationship is clear and direct. The more mining you have upstream, the higher the biological loss and salinity levels will be downstream, and the farther they will extend."
Numerous recent studies have demonstrated the water-quality problems caused at or near the site of individual surface coal mines, Bernhardt noted. She and her team "set out to understand how the large and growing number of surface mines is affecting water quality throughout Appalachia."
They used NASA satellite images and computer data to map the extent of surface mining taking place across a 12,000-square-mile area of the southern West Virginia coalfields between 1976 and 2005.
They found that companies had converted more than five percent of the land into mine sites and buried 480 miles of streams beneath adjacent valley fills during this period.
Chemical and biological data from 223 streams sampled by the West Virginia Department of Environmental Protection between 1997 and 2007 were combined with mapping to help the researchers determine that pollution runoff from the mines could substantially degrade more than 1,400 miles of streams in the region. That's four times the length of streams buried by the valley fills.
"It's important to recognize that surface coal mining pollution doesn't stop at mine-permit boundaries," said Brian D. Lutz, a postdoctoral associate in Bernhardt's lab.
"Our analysis suggests that mining only five percent of the land surface is degrading between 22 percent and 32 percent of the region's rivers," he said.
Substantial declines in insect diversity began to occur when companies had mined as little as one percent of upstream land, the analysis showed. In areas where companies had converted about five percent of the land into mines, sensitive species such as mayflies and stoneflies had vanished or declined to an extent that the streams would qualify as biologically impaired under criteria set by the state of West Virginia.
The designation means the streams could be placed on a list of waterways that the state must take steps to rehabilitate.
"What is so compelling is that we found many different types of organisms are lost downstream of surface coal mines, and most of them begin to disappear at similar levels of mining," said Ryan S. King, associate professor of biology at Baylor. "Our analysis shows that coal mining is leading to widespread declines in aquatic biodiversity in Appalachian streams."
###
Lutz and King co-authored the paper with Bernhardt. Other coauthors were John P. Fay, instructor of geospatial analysis at the Nicholas School; Catherine E. Carter, a 2010 master's graduate of the Nicholas School, now at TetraTech; Ashley M. Helton, postdoctoral associate in Duke's Department of Biology; John Amos of SkyTruth; and David Campagna, of Campagna & Associates.
The study was supported by unrestricted gifts in support of research from The Foundation for the Carolinas and the Sierra Club, and through a contract to Amos and Campagna from Appalachian Voices.
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Public release date: 30-Jul-2012
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